Description

3,6-Dibromo-2-Fluorophenylboronic Acid is a high-purity organoboron building block, specifically a fluorinated and brominated phenylboronic acid derivative. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, enabling the efficient synthesis of complex biaryl structures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and production of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the dibromo-fluorophenyl moiety is required.
• Material Science Research: Serves as a precursor for creating novel organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Cross-Coupling Reactions: Primarily designed for use in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds under mild conditions.
• Ligand and Catalyst Development: Acts as a starting material for the preparation of specialized ligands used in asymmetric catalysis.

Basic Information

Product Name	3,6-Dibromo-2-Fluorophenylboronic Acid
CAS No.	870778-92-0
Molecular Formula	C6H4BBr2FO2
Molecular Weight	297.71 g/mol
Synonyms	(3,6-Dibromo-2-fluorophenyl)boronic acid; 2-Fluoro-3,6-dibromophenylboronic acid; B-(3,6-Dibromo-2-fluorophenyl)boronic acid; 870778-92-0; Boronic acid, B-(3,6-dibromo-2-fluorophenyl)-; 3,6-Dibromo-2-fluorobenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3,6-Dibromo-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and support your regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This material is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Titration)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.