Description

5-Acetyl-2-Fluorophenylboronic Acid is a specialized organoboron compound featuring both acetyl and fluorine substituents on the aromatic ring. This unique structure makes it a valuable high-purity building block for advanced organic synthesis, particularly in cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing fluorinated drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed as a versatile boronic acid reagent for constructing complex, multi-substituted biaryl systems in medicinal and process chemistry.
• Diagnostic Reagents: Potential use in developing fluorescent probes and sensor molecules due to its functionalizable acetyl group.

Basic Information

Product Name	5-Acetyl-2-Fluorophenylboronic Acid
CAS No.	870777-29-0
Molecular Formula	C8H8BFO3
Molecular Weight	181.96 g/mol
Synonyms	(5-Acetyl-2-fluorophenyl)boronic acid; 2-Fluoro-5-acetylbenzeneboronic acid; 5-Acetyl-2-fluorobenzeneboronic acid; Boronic acid, B-(5-acetyl-2-fluorophenyl)-; 870777-29-0; AKOS005258155; FT-0778938
EINECS	Contact for details

Quality Control

Our 5-Acetyl-2-Fluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.