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2-Fluoro-6-Iodophenylboronic Acid CAS NO 870777-22-3


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CAS No.:870777-22-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Fluoro-6-Iodophenylboronic Acid is a versatile and highly functionalized boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in the unique combination of halogen and boronic acid functional groups, enabling precise cross-coupling reactions to construct complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs) and novel organic electronic materials.

Application

  • Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
  • Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products by facilitating the formation of biaryl structures.
  • Material Science Research: Employed in the development of organic light-emitting diodes (OLEDs), liquid crystals, and conductive polymers due to its halogenated aromatic core.
  • Chemical Biology & Proteomics: Acts as a handle for bioconjugation and the development of chemical probes and inhibitors targeting specific enzymes.
  • Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
  • Custom Synthesis & Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex, high-value molecules for clients.

Basic Information

Product Name 2-Fluoro-6-Iodophenylboronic Acid
CAS No. 870777-22-3
Molecular Formula C6H5BFIO2
Molecular Weight 265.82 g/mol
Synonyms (2-Fluoro-6-iodophenyl)boronic acid; 2-Fluoro-6-iodobenzeneboronic acid; Boronic acid, B-(2-fluoro-6-iodophenyl)-; 870777-22-3; 2-Fluoro-6-iodophenyl-B(OH)2; 2-Iodo-6-fluorophenylboronic acid
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Quality Control

Our 2-Fluoro-6-Iodophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, supporting compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item Specification
Appearance White to off-white powder or crystalline solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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