Description

2-Butoxy-6-Fluorophenylboronic Acid is a specialized organoboron compound used as a key building block in advanced organic synthesis. Its value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing fluorinated biaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific fluorinated aromatic systems.
• Material Science Research: Serves as a monomer or building block for creating novel organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and other boron-containing catalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring precise boronic acid derivatives.

Basic Information

Product Name	2-Butoxy-6-Fluorophenylboronic Acid
CAS No.	870777-19-8
Molecular Formula	C₁₀H₁₄BFO₃
Molecular Weight	212.03 g/mol
Synonyms	(2-Butoxy-6-fluorophenyl)boronic acid; 2-Fluoro-6-butoxyphenylboronic acid; B-(2-Butoxy-6-fluorophenyl)boronic acid; 6-Fluoro-2-butoxybenzeneboronic acid; 870777-19-8; (2-Butoxy-6-fluorophenyl)boronic acid (ACI); AKOS005258065
EINECS	Contact for details

Quality Control

Every batch of 2-Butoxy-6-Fluorophenylboronic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B) and HPLC, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere (e.g., nitrogen or argon) to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.