Description

6-Fluorochromone-3-Propionic Acid is a specialized fluorinated chromone derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique fluorinated chromone scaffold enables precise molecular modifications. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the synthesis of potential drug candidates targeting various enzymes and receptors.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel active pharmaceutical ingredients (APIs), especially in oncology and CNS drug discovery programs.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the bioactivity of the chromone core.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating fluorescent probes or activity-based protein profiling (ABPP) reagents due to its fluorophore potential.
• Material Science Precursor: Employed in the synthesis of advanced organic materials, such as organic semiconductors or specialty polymers with tailored optical properties.
• Academic & Contract Research: Essential for academic research and contract research organizations (CROs) conducting structure-activity relationship (SAR) studies.

Basic Information

Product Name	6-Fluorochromone-3-Propionic Acid
CAS No.	870704-01-1
Molecular Formula	C₁₂H₉FO₄
Molecular Weight	236.20 g/mol
Synonyms	3-(6-Fluorochromon-3-yl)propanoic acid; 6-Fluoro-3-(2-carboxyethyl)chromone; 6-Fluoro-3-(3-oxo-3-propanoic acid)chromone; 6-Fluorochromone-3-propanoic acid; 6-Fluoro-4-oxo-4H-chromene-3-propionic acid; 6-Fluoro-4-oxo-4H-1-benzopyran-3-propanoic acid; 870704-01-1 (CAS Name)
EINECS	Contact for details

Quality Control

Our 6-Fluorochromone-3-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.