Description

cis-2-tert-Butoxycarbonylamino-Cyclohex-3-Enecarboxylic Acid CAS NO 870288-16-7 is a protected amino acid derivative featuring both a Boc-protected amine and a carboxylic acid functional group on a cyclohexene scaffold. This compound serves as a crucial chiral building block and advanced pharmaceutical intermediate, enabling the synthesis of complex, biologically active molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide mimetics, protease inhibitors, and other active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Organic Synthesis Building Block: Employed in asymmetric synthesis and medicinal chemistry for constructing complex, functionalized cyclohexane and cyclohexene ring systems.
• Peptidomimetic Development: Facilitates the creation of conformationally constrained peptide analogs for drug discovery programs targeting various diseases.
• Chemical Biology Probes: Acts as a precursor for labeled compounds or molecular probes used in biochemical and cellular studies.
• Catalyst and Ligand Synthesis: Serves as a starting material for the preparation of chiral ligands and organocatalysts used in enantioselective transformations.

Basic Information

Product Name	cis-2-tert-Butoxycarbonylamino-Cyclohex-3-Enecarboxylic Acid
CAS No.	870288-16-7
Molecular Formula	C12H19NO4
Molecular Weight	241.28 g/mol
Synonyms	(1R,2S,6S)-2-[(tert-Butoxycarbonyl)amino]-4-cyclohexene-1-carboxylic acid; (1R,2S,6S)-2-(Boc-amino)-4-cyclohexene-1-carboxylic acid; cis-2-(Boc-amino)cyclohex-3-ene-1-carboxylic acid; 2-[(tert-Butoxycarbonyl)amino]cyclohex-3-ene-1-carboxylic acid; cis-2-(tert-Butoxycarbonylamino)cyclohex-3-enecarboxylic acid; Boc-ACHC-OH; (1R,2S,6S)-2-(tert-Butoxycarbonylamino)cyclohex-4-ene-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our cis-2-tert-Butoxycarbonylamino-Cyclohex-3-Enecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.