Description

2'-Dicyclohexylphosphino-2,6-Di-I-Propyl-4-Sulfonato-1,1'-Biphenylhydratesodiumsalt is a high-value, water-soluble phosphine ligand, a key component in modern transition-metal catalysis. Its sulfonated biphenyl backbone provides excellent solubility in aqueous and polar organic media, enabling efficient and environmentally friendlier catalytic processes. This ligand is essential for researchers and process chemists in the pharmaceutical, fine chemical, and agrochemical industries, where it facilitates challenging cross-coupling reactions like Suzuki-Miyaura and Buchwald-Hartwig aminations under mild conditions.

Application

• Homogeneous Catalysis: As a critical ligand for palladium, rhodium, and ruthenium catalysts in cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira).
• Pharmaceutical Intermediate Synthesis: Enabling the construction of complex biaryl and heteroaryl scaffolds for active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the synthesis of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: For the precise synthesis of specialty chemicals, flavors, fragrances, and electronic materials.
• Aqueous-Phase Catalysis: Facilitating green chemistry initiatives by allowing catalytic cycles to proceed in water, reducing organic solvent waste.
• Academic & Industrial R&D: A versatile tool for developing new catalytic methodologies and optimizing existing synthetic routes.

Basic Information

Product Name	2'-Dicyclohexylphosphino-2,6-Di-I-Propyl-4-Sulfonato-1,1'-Biphenylhydratesodiumsalt
CAS No.	870245-84-4
Molecular Formula	C30H43NaO4PS
Molecular Weight	577.68 g/mol
Synonyms	Sodium 2'-Dicyclohexylphosphino-2,6-diisopropyl-4-sulfonato-1,1'-biphenyl hydrate; 2-Dicyclohexylphosphino-2',6'-diisopropoxybiphenyl-3-sulfonic acid sodium salt; Sulfonated XPhos; Sodium XPhos Sulfonate; XPhos-SO3Na; 2-Dicyclohexylphosphino-2',6'-di-i-propoxy-1,1'-biphenyl-3-sulfonic acid sodium salt; Water-Soluble XPhos Ligand; Na-XPhos-SO3
EINECS	Contact for details

Quality Control

Our production of 2'-Dicyclohexylphosphino-2,6-Di-I-Propyl-4-Sulfonato-1,1'-Biphenylhydratesodiumsalt adheres to stringent quality protocols to ensure batch-to-batch consistency and high catalytic performance. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and elemental analysis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support cGMP manufacturing requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and opened under an inert atmosphere (e.g., nitrogen or argon) for prolonged handling to prevent moisture uptake and potential degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.