Description

3-Hydroxy-4-Methyl-N-[3-(Trifluoromethyl)Phenyl]Benzamide is a high-purity, specialized benzamide derivative featuring a trifluoromethylphenyl substituent, a structure of significant interest in advanced organic synthesis. This compound matters as a critical building block or intermediate for developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group is prized for its ability to modulate bioavailability and metabolic stability. It is primarily needed by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and material science sectors for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used as a precursor in the formulation of advanced herbicides and pesticides, leveraging the bioactivity of the trifluoromethyl group.
• Chemical Research: Acts as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or liquid crystals where fluorinated aromatic units are required.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	3-Hydroxy-4-Methyl-N-[3-(Trifluoromethyl)Phenyl]Benzamide
CAS No.	870221-73-1
Molecular Formula	C15H12F3NO2
Molecular Weight	295.26 g/mol
Synonyms	3-Hydroxy-4-methyl-N-[3-(trifluoromethyl)phenyl]benzamide; 4-Methyl-3-hydroxy-N-[3-(trifluoromethyl)phenyl]benzamide; N-(3-(Trifluoromethyl)phenyl)-3-hydroxy-4-methylbenzamide; 3-Hydroxy-4-methylbenzoic acid (3-trifluoromethyl)anilide; Benzamide, 3-hydroxy-4-methyl-N-[3-(trifluoromethyl)phenyl]-; 870221-73-1; CAS 870221-73-1
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-4-Methyl-N-[3-(Trifluoromethyl)Phenyl]Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.