Description

2-Amino-6-Trifluoromethyl-Benzamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl-substituted benzamide structure. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring enhanced metabolic stability and bioavailability. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science: Employed in the research and production of advanced polymers and functional materials with specific electronic or surface properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Item	Detail
Product Name	2-Amino-6-Trifluoromethyl-Benzamide
CAS No.	869936-81-2
Molecular Formula	C8H7F3N2O
Molecular Weight	204.15 g/mol
Synonyms	2-Amino-6-(trifluoromethyl)benzamide; 6-(Trifluoromethyl)anthranilamide; 2-Amino-alpha,alpha,α-trifluoro-o-toluamide; Benzamide, 2-amino-6-(trifluoromethyl)-; 2-Amino-6-trifluoromethylbenzamide; 869936-81-2; 2-Amino-α,α,α-trifluoro-o-toluamide
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Trifluoromethyl-Benzamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.