Description

3-{[(tert-Butoxy)Carbonyl]Amino}Oxolane-3-Carboxylic Acid is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and peptide mimetics. Pharmaceutical R&D departments, agrochemical innovators, and specialty chemical manufacturers need this reliable intermediate to streamline their synthetic routes and ensure product quality.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly for protease inhibitors and other biologically active molecules.
• Peptidomimetics & PROTACs: Used to introduce constrained, heterocyclic amino acid scaffolds into peptide backbones or as linkers in proteolysis-targeting chimeras (PROTACs).
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and plant growth regulators with enhanced specificity.
• Material Science: Potential monomer or cross-linking agent for creating specialty polymers with unique thermal or mechanical properties.
• Chemical Biology Probes: Utilized in the development of activity-based probes and other tools for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects requiring high-fidelity, Boc-protected intermediates.

Basic Information

Product Name	3-{[(tert-Butoxy)Carbonyl]Amino}Oxolane-3-Carboxylic Acid
CAS No.	869785-31-9
Molecular Formula	C10H17NO5
Molecular Weight	231.25 g/mol
Synonyms	3-((tert-Butoxycarbonyl)amino)tetrahydrofuran-3-carboxylic acid; 3-(Boc-amino)oxolane-3-carboxylic acid; 3-(Boc-amino)tetrahydrofuran-3-carboxylic acid; Boc-3-aminooxolane-3-carboxylic acid; 3-Amino-3-carboxytetrahydrofuran N-Boc derivative; (3-Oxolanyl)-Boc-aminoacetic acid derivative; 869785-31-9
EINECS	Contact for details

Quality Control

Our 3-{[(tert-Butoxy)Carbonyl]Amino}Oxolane-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade starting materials and compliance with ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.