Description

1H-Inden-1-Ol, 2,3-Dihydro-5-(Trifluoromethyl)- is a high-value, fluorinated indanol derivative, a crucial chiral building block in advanced organic synthesis. Its core value lies in its unique molecular scaffold, which incorporates a trifluoromethyl group—a key motif known to enhance the metabolic stability, lipophilicity, and bioavailability of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the construction of advanced herbicides and pesticides, where the trifluoromethyl group imparts improved biological activity and environmental persistence.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic electronic materials due to its fused ring system and fluorine content.
• Chemical Biology Probes: Utilized as a building block for developing molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	1H-Inden-1-Ol, 2,3-Dihydro-5-(Trifluoromethyl)-
CAS No.	869725-57-5
Molecular Formula	C10H9F3O
Molecular Weight	202.17 g/mol
Synonyms	5-(Trifluoromethyl)-2,3-dihydro-1H-inden-1-ol; 5-(Trifluoromethyl)indan-1-ol; 2,3-Dihydro-5-(trifluoromethyl)-1H-inden-1-ol; 1H-Inden-1-ol, 2,3-dihydro-5-(trifluoromethyl)-; 869725-57-5; 5-Trifluoromethylindan-1-ol; (1-Hydroxy-5-trifluoromethyl-indanyl); 5-(Trifluoromethyl)-1-indanol
EINECS	Contact for details

Quality Control

Our 1H-Inden-1-Ol, 2,3-Dihydro-5-(Trifluoromethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, NMR, and MS for structural confirmation, to ensure it meets the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.