Description

2-Bromo-1-(4-Bromo-2-Fluorophenyl)Ethanone is a high-purity, multi-functional halogenated aromatic ketone building block. This compound is valued for its precise molecular architecture, enabling the synthesis of complex molecules in advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D teams, as well as by fine chemical manufacturers, for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a crucial precursor for novel herbicides, fungicides, and insecticides, leveraging the fluorine and bromine substituents for enhanced bioactivity and environmental stability.
• Material Science Research: Used in the synthesis of advanced organic materials, including liquid crystals, organic semiconductors, and photoactive polymers.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) due to the reactive bromine atoms, facilitating complex molecular assembly.
• Fluorine Chemistry Studies: A valuable compound for investigating structure-activity relationships (SAR) in medicinal chemistry, where the ortho-fluorine atom influences pharmacokinetic properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	2-Bromo-1-(4-Bromo-2-Fluorophenyl)Ethanone
CAS No.	869569-77-7
Molecular Formula	C8H5Br2FO
Molecular Weight	295.93 g/mol
Synonyms	1-(4-Bromo-2-fluorophenyl)-2-bromoethanone; 2-Bromo-1-(4-bromo-2-fluorophenyl)ethan-1-one; 4'-Bromo-2'-fluoro-2-bromoacetophenone; α,4-Dibromo-2-fluoroacetophenone; 2-Bromo-4'-bromo-2'-fluoroacetophenone; 869569-77-7; Ethanone, 2-bromo-1-(4-bromo-2-fluorophenyl)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(4-Bromo-2-Fluorophenyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring traceability and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.