Description

1-Boc-2,2-Dimethylpyrrolidine is a high-purity, protected amine building block essential for advanced organic synthesis. Its primary value lies in providing a sterically hindered, nitrogen-containing scaffold that is readily deprotected under acidic conditions, enabling the controlled introduction of complex amine functionalities. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require sterically defined amine components.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Integral for creating proline analogs and other conformationally restricted peptide mimics in medicinal chemistry.
• Polymer Chemistry: Employed as a monomer or chain modifier in the synthesis of specialty polyamides and other functional polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1-Boc-2,2-Dimethylpyrrolidine
CAS No.	869527-80-0
Molecular Formula	C11H21NO2
Molecular Weight	199.29 g/mol
Synonyms	tert-Butyl 2,2-dimethylpyrrolidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-2,2-dimethylpyrrolidine; 2,2-Dimethyl-1-Boc-pyrrolidine; 1-Boc-2,2-dimethylpyrrolidine; N-Boc-2,2-dimethylpyrrolidine; 1-N-Boc-2,2-dimethylpyrrolidine; Pyrrolidine, 2,2-dimethyl-, 1-(1,1-dimethylethyl) ester; 869527-80-0
EINECS	Contact for details

Quality Control

Our 1-Boc-2,2-Dimethylpyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.