Description

3-(4,4-Difluoropiperidin-1-Yl)Propan-1-Amine is a high-purity, advanced pharmaceutical intermediate featuring a difluorinated piperidine scaffold. This compound is valued for its role in modulating the physicochemical and metabolic properties of active pharmaceutical ingredients, making it a critical building block in modern drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in the areas of central nervous system (CNS) and metabolic disease targets.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of bioactive molecules and active pharmaceutical ingredients (APIs).
• Drug Discovery & Medicinal Chemistry: Used as a versatile building block for constructing compound libraries and optimizing lead candidates, especially where fluorine substitution is desired for improved potency and metabolic stability.
• CNS Drug Development: Employed in the research and synthesis of potential therapeutics targeting neurological disorders.
• Agrochemical Research: Serves as an intermediate in the development of novel pesticides and herbicides.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied for bespoke synthesis projects requiring high-purity, specialized fluorine-containing intermediates.

Basic Information

Item	Detail
Product Name	3-(4,4-Difluoropiperidin-1-Yl)Propan-1-Amine
CAS No.	869493-53-8
Molecular Formula	C8H16F2N2
Molecular Weight	178.22 g/mol
Synonyms	1-(3-Aminopropyl)-4,4-difluoropiperidine; 4,4-Difluoro-1-(3-aminopropyl)piperidine; 3-(4,4-Difluoropiperidino)propylamine; 869493-53-8; 4,4-Difluoro-N-(3-aminopropyl)piperidine; Propan-1-amine, 3-(4,4-difluoropiperidin-1-yl)-; 3-(4,4-Difluoro-1-piperidinyl)-1-propanamine
EINECS	Contact for details

Quality Control

Every batch of 3-(4,4-Difluoropiperidin-1-Yl)Propan-1-Amine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.