Description

Catasium(R) T2(R), 3-{(1R,4S)-3-[Bis(3,5-Dimethylphenyl)Phosphanyl]-1,7,7-Trimethylbicyclo[2.2.1]Hept-2-En-2-Yl}-4-Diphenylphosphanyl-2,5-Dimethylthiophene is a high-performance, chiral phosphine ligand designed for asymmetric catalysis. Its value lies in providing exceptional enantioselectivity and catalytic activity in complex synthetic transformations, enabling the production of high-purity chiral intermediates. This product is essential for R&D and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable and efficient chiral induction.

Application

• Asymmetric Hydrogenation: A key ligand for the enantioselective reduction of prochiral olefins, enamines, and ketones in pharmaceutical API synthesis.
• Cross-Coupling Reactions: Employed in asymmetric versions of Suzuki-Miyaura, Heck, and other C-C bond-forming reactions to construct chiral scaffolds.
• Asymmetric Allylic Alkylation: Facilitates the creation of stereogenic centers through nucleophilic substitution with high enantiomeric excess.
• Hydroformylation: Used in the development of chiral aldehydes from olefins, a critical step for flavors, fragrances, and pharmaceutical building blocks.
• Academic & Industrial R&D: A valuable tool for developing novel catalytic methodologies and exploring new synthetic routes to chiral molecules.
• Process Chemistry Optimization: Implemented in scale-up and process development to improve yield, selectivity, and cost-efficiency of chiral manufacturing.

Basic Information

Product Name	Catasium(R) T2(R), 3-{(1R,4S)-3-[Bis(3,5-Dimethylphenyl)Phosphanyl]-1,7,7-Trimethylbicyclo[2.2.1]Hept-2-En-2-Yl}-4-Diphenylphosphanyl-2,5-Dimethylthiophene
CAS No.	868851-48-3
Molecular Formula	C53H56P2S
Molecular Weight	763.00 g/mol
Synonyms	Catasium T2; (1R,4S)-3-[Bis(3,5-dimethylphenyl)phosphanyl]-1,7,7-trimethylbicyclo[2.2.1]hept-2-en-2-yl-4-diphenylphosphanyl-2,5-dimethylthiophene; T2 Ligand; Catasium T2 Ligand; Chiral Bicyclo[2.2.1]heptene Phosphine Ligand; (R)-Catasium T2; (1R,4S)-Catasium T2; Josiphos-type Ligand Derivative
EINECS	Contact for details

Quality Control

Every batch of Catasium(R) T2(R) is manufactured and tested under strict quality management systems to ensure consistency and performance. We provide comprehensive Certificates of Analysis (COA) detailing purity, chiral integrity, and key specifications. Our quality protocols are designed to meet the stringent requirements of cGMP and ISO standards for advanced pharmaceutical intermediates and catalyst applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to maintain stability and prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.