Description

4-Bromo-2-Methylbenzamide is a versatile brominated aromatic amide building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a bromine substituent and an amide functional group, makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders or as kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging the bromine atom for further functionalization.
• Ligand and Catalyst Development: Acts as a building block for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers where brominated aromatics are required.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	4-Bromo-2-Methylbenzamide
CAS No.	868776-08-3
Molecular Formula	C8H8BrNO
Molecular Weight	214.06 g/mol
Synonyms	2-Methyl-4-bromobenzamide; 4-Bromo-o-toluamide; Benzamide, 4-bromo-2-methyl-; 4-Bromo-2-methyl-benzoic acid amide; 868776-08-3; AI3-26033; BRN 2206656; SCHEMBL1550621; ZINC000004079773
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure every batch of 4-Bromo-2-Methylbenzamide meets the highest standards of purity and consistency. Our quality control protocols include advanced analytical techniques such as HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.