Description

Ethyl 3-(2,3-Difluorophenyl)-3-Oxopropanoate is a high-purity fluorinated organic building block, specifically a β-keto ester derivative. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the difluorophenyl moiety can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for methodology development, including cross-coupling reactions and cyclization studies.
• Ligand and Catalyst Preparation: Useful for synthesizing complex chelating ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Ethyl 3-(2,3-Difluorophenyl)-3-Oxopropanoate
CAS No.	868611-68-1
Molecular Formula	C11H10F2O3
Molecular Weight	228.19 g/mol
Synonyms	Ethyl 2,3-Difluorobenzoylacetate; Ethyl (2,3-Difluorobenzoyl)acetate; 3-Oxobutanoic acid, 3-(2,3-difluorophenyl)-, ethyl ester; Ethyl 3-oxo-3-(2,3-difluorophenyl)propanoate; 868611-68-1; AKOS005258991; 2,3-Difluorophenyl β-ketopropionate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(2,3-Difluorophenyl)-3-Oxopropanoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.