Description

3-Bromo-5-Fluoro-2-Propoxyphenylboronic acid is a high-purity, multi-functional boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its unique halogenated and alkoxylated aromatic structure, which enables precise cross-coupling reactions for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex target molecules under cGMP conditions.

Basic Information

Product Name	3-Bromo-5-Fluoro-2-Propoxyphenylboronic acid
CAS No.	868272-84-8
Molecular Formula	C9H11BBrFO3
Molecular Weight	275.90 g/mol
Synonyms	(3-Bromo-5-fluoro-2-propoxyphenyl)boronic acid; 2-Propoxyphenylboronic acid, 3-bromo-5-fluoro-; Boronic acid, B-(3-bromo-5-fluoro-2-propoxyphenyl)-; 3-Bromo-5-fluoro-2-propoxybenzeneboronic acid; 868272-84-8; AKOS025310947; BRN 29329331; FT-0698081
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoro-2-Propoxyphenylboronic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.