Description

Pantoprazole Sulfide-B-D-Glucuronide is a key metabolite and synthetic intermediate of the proton pump inhibitor pantoprazole. This compound is of significant importance for pharmaceutical research and development, particularly in the study of drug metabolism, pharmacokinetics, and the synthesis of high-purity active pharmaceutical ingredients (APIs). It is primarily required by pharmaceutical manufacturers, analytical laboratories, and research institutions engaged in the development and quality control of pantoprazole and related therapeutic agents.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for the quantitative and qualitative analysis of pantoprazole and its metabolites in biological matrices and finished drug products.
• Metabolite Research: Critical for in-vitro and in-vivo studies to understand the metabolic pathways, bioavailability, and excretion profile of pantoprazole.
• API Synthesis Intermediate: Used as a high-purity building block in the advanced stages of synthesizing pantoprazole sodium sesquihydrate and related compounds.
• Analytical Method Development: Essential for developing and validating sensitive HPLC, LC-MS, or GC-MS methods for impurity profiling and assay determination.
• Regulatory Compliance & Documentation: Supports regulatory filings (e.g., with FDA, EMA) by providing definitive characterization data for drug substances and products.
• Quality Control & Assurance: Employed in pharmaceutical QC labs to identify and quantify related substances and degradation products, ensuring batch-to-batch consistency and purity.

Basic Information

Product Name	Pantoprazole Sulfide-B-D-Glucuronide
CAS No.	867300-67-2
Molecular Formula	C23H27FN4O9S
Molecular Weight	554.55 g/mol
Synonyms	Pantoprazole Sulfide Glucuronide; Pantoprazole Metabolite (Sulfide Glucuronide); 5-(Difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole β-D-Glucuronide (Sulfide Form); BY1023 Sulfide Glucuronide; SK&F96022 Sulfide Glucuronide; Pantoprazole Sulfide β-D-Glucuronide; Pantoprazole Sulfide-β-D-Glucopyranuronic Acid
EINECS	Contact for details

Quality Control

Our Pantoprazole Sulfide-B-D-Glucuronide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure compliance with high-grade pharmaceutical standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.