Description

2-Fluoro-5-Iodophenylboronic Acid is a high-value organoboron building block, specifically a halogenated phenylboronic acid derivative. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex biaryl structures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex fluorinated and iodinated aromatic systems.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by constructing specific biaryl backbones critical for biological activity.
• Material Science Research: Serves as a precursor in the development of organic light-emitting diodes (OLEDs), liquid crystals, and other advanced organic electronic materials.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and imaging agents for biochemical and diagnostic applications.
• Cross-Coupling Reactions: Primarily designed for use in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds with high efficiency and selectivity.
• Library Synthesis for Drug Discovery: Enables the rapid generation of diverse compound libraries for high-throughput screening in medicinal chemistry programs.

Basic Information

Product Name	2-Fluoro-5-Iodophenylboronic Acid
CAS No.	866683-41-2
Molecular Formula	C6H5BFO2I
Molecular Weight	265.82 g/mol
Synonyms	(2-Fluoro-5-iodophenyl)boronic acid; 2-Fluoro-5-iodobenzeneboronic acid; 5-Iodo-2-fluorophenylboronic acid; Boronic acid, B-(2-fluoro-5-iodophenyl)-; 866683-41-2; 2-Fluoro-5-iodo phenylboronic acid; (5-Iodo-2-fluorophenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Iodophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.