Description

1-[(5-Hydroxy-2-Pyridinyl)Carbonyl]-Piperidine is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine and hydroxypyridine structural motifs. This compound is of significant commercial value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, particularly those targeting the central nervous system.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing complex molecular architectures containing nitrogen heterocycles.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand and Catalyst Development: Potential utility in the development of novel ligands or organocatalysts due to its coordinating nitrogen atoms.

Basic Information

Product Name	1-[(5-Hydroxy-2-Pyridinyl)Carbonyl]-Piperidine
CAS No.	866327-65-3
Molecular Formula	C11H14N2O2
Molecular Weight	206.24 g/mol
Synonyms	1-(5-Hydroxypyridine-2-carbonyl)piperidine; 1-(5-Hydroxy-2-pyridinyl)carbonylpiperidine; 1-(5-Hydroxypicolinoyl)piperidine; Piperidine, 1-[(5-hydroxy-2-pyridinyl)carbonyl]-; 5-Hydroxy-N-(piperidin-1-yl)picolinamide; 866327-65-3
EINECS	Contact for details

Quality Control

Our production of 1-[(5-Hydroxy-2-Pyridinyl)Carbonyl]-Piperidine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is released with a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical development, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for extended periods to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.