Description

(1S,3S,5S)-2-Azabicyclo[3.1.0]Hexane-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate featuring a unique constrained bicyclic structure. This compound is valued for its role as a critical chiral building block in the synthesis of complex, biologically active molecules. It is primarily sought by research and development teams in the pharmaceutical and biotechnology sectors for the creation of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs).
• Drug Discovery & Medicinal Chemistry: Used as a rigid scaffold to explore structure-activity relationships (SAR) and develop new chemical entities.
• CNS-Targeted Therapeutics: Serves as a precursor in the development of compounds targeting neurological pathways.
• Antiviral Agent Synthesis: Employed in research for constructing novel antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in stereoselective chemical transformations.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale manufacturing of clinical trial materials.

Basic Information

Product Name	(1S,3S,5S)-2-Azabicyclo[3.1.0]Hexane-3-Carbonitrile
CAS No.	866083-42-3
Molecular Formula	C7H8N2
Molecular Weight	120.15 g/mol
Synonyms	(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carbonitrile; (1S,3S,5S)-3-Cyano-2-azabicyclo[3.1.0]hexane; (1S,3S,5S)-3-Cyanobicyclo[3.1.0]hexan-2-amine; 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, (1S,3S,5S)-; Rel-(1S,3S,5S)-2-Azabicyclo[3.1.0]hexane-3-carbonitrile
EINECS	Contact for details

Quality Control

Our (1S,3S,5S)-2-Azabicyclo[3.1.0]Hexane-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.