Description

(1S,2R)-2-(tert-Butoxycarbonylamino)Cyclohexanecarboxylic Acid is a high-purity, chiral building block essential for advanced organic synthesis. This compound is a critical intermediate in the development of active pharmaceutical ingredients (APIs) and complex bioactive molecules, where stereochemical integrity is paramount. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in peptide mimetics, protease inhibitor synthesis, and other sophisticated medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly in protease inhibitor and peptidomimetic drug discovery programs.
• Peptide Chemistry: Used in the preparation of conformationally constrained, non-natural amino acid derivatives for peptide backbone modification and stabilization.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in catalytic asymmetric reactions to construct complex molecular architectures.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes, enzyme inhibitors, and other tools for biochemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: A critical component for fine chemical suppliers and CDMOs (Contract Development and Manufacturing Organizations) producing custom intermediates under cGMP conditions.

Basic Information

Product Name	(1S,2R)-2-(tert-Butoxycarbonylamino)Cyclohexanecarboxylic Acid
CAS No.	865689-36-7
Molecular Formula	C12H21NO4
Molecular Weight	243.30 g/mol
Synonyms	(1S,2R)-2-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic acid; (1S,2R)-Boc-Amino-cyclohexanecarboxylic acid; (1S,2R)-2-(Boc-amino)cyclohexanecarboxylic acid; trans-2-(Boc-amino)cyclohexanecarboxylic acid (1S,2R)-; Boc-(1S,2R)-ACHC-OH; Cyclohexanecarboxylic acid, 2-[(1,1-dimethylethoxy)carbonyl]amino]-, (1S,2R)-
EINECS	Contact for details

Quality Control

Our (1S,2R)-2-(tert-Butoxycarbonylamino)Cyclohexanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial methods for identity and assay, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.