Description

Rac trans-n-Boc-Pyrrolidine-3,4-Dicarboxylic Acid is a protected pyrrolidine derivative that serves as a versatile chiral building block in advanced organic synthesis. This compound is critical for the development of novel pharmaceuticals and agrochemicals, enabling the precise construction of complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries for applications in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other bioactive molecules.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to discover new drug candidates.
• Peptidomimetic Synthesis: Serves as a constrained scaffold for designing and synthesizing peptide analogs with enhanced metabolic stability and bioavailability.
• Agrochemical Development: Employed as a building block in the research and production of advanced herbicides and fungicides.
• Ligand and Catalyst Preparation: Useful for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Rac trans-n-Boc-Pyrrolidine-3,4-Dicarboxylic Acid
CAS No.	865451-68-9
Molecular Formula	C12H19NO6
Molecular Weight	273.28 g/mol
Synonyms	trans-1-Boc-3,4-pyrrolidinedicarboxylic acid; (±)-trans-1-(tert-Butoxycarbonyl)-3,4-pyrrolidinedicarboxylic acid; rac-trans-1-N-Boc-3,4-pyrrolidinedicarboxylic acid; 1-Boc-3,4-pyrrolidinedicarboxylic acid (racemic trans); NSC 758663; tert-Butyl 3,4-dicarboxypyrrolidine-1-carboxylate (racemic trans isomer); Pyrrolidine-3,4-dicarboxylic acid, 1-(1,1-dimethylethyl) ester, (3R,4S)-rel-
EINECS	Contact for details

Quality Control

Our Rac trans-n-Boc-Pyrrolidine-3,4-Dicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.