Description

Ethyl 3-(4-Amino-2-Fluorophenyl)Propanoate CAS NO 865137-77-5 is a high-purity fluorinated aromatic ester building block of significant importance in advanced organic synthesis. Its core value lies in its bifunctional structure, featuring both a reactive amino group and a protected carboxylic acid equivalent, enabling its use in constructing complex molecular architectures. This compound is primarily needed by research and development chemists and process scale-up teams within the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated aromatic cores in advanced electronic and display materials.
• Peptidomimetics & Bio-conjugation: The ethyl ester and amino group allow for incorporation into peptide analogs or for creating linker molecules in bioconjugation chemistry.
• Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific custom synthesis projects.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological development and exploring new fluorination chemistry.

Basic Information

Product Name	Ethyl 3-(4-Amino-2-Fluorophenyl)Propanoate
CAS No.	865137-77-5
Molecular Formula	C11H14FNO2
Molecular Weight	211.23 g/mol
Synonyms	Ethyl 3-(4-Amino-2-fluorophenyl)propionate; 2-Fluoro-4-(3-ethoxy-3-oxopropyl)aniline; 3-(4-Amino-2-fluorophenyl)propionic Acid Ethyl Ester; 4-Amino-2-fluorobenzene propanoic acid ethyl ester; Ethyl 4-Amino-2-fluorohydrocinnamate; 865137-77-5; Ethyl 3-(4-Amino-2-Fluorophenyl)Propanoate
EINECS	Contact for details

Quality Control

Our Ethyl 3-(4-Amino-2-Fluorophenyl)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.