Description

3-Methyl-4-Trifluoromethyl-Phenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. Its value lies in enabling the efficient construction of complex molecules through pivotal cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing drug candidates, particularly those requiring the trifluoromethyl group for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the unique 3-methyl-4-trifluoromethylphenyl moiety can impart specific biological activity.
• Material Science: Serves as a precursor for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura couplings to form biaryl and other carbon-carbon bonds with high efficiency and selectivity.
• Chemical Research: A versatile reagent in academic and industrial R&D labs for methodology development and the synthesis of complex organic molecules.
• Ligand and Catalyst Development: Can be utilized to create novel boronic acid-based ligands for catalysis or sensing applications.

Basic Information

Product Name	3-Methyl-4-Trifluoromethyl-Phenylboronic Acid
CAS No.	864759-67-1
Molecular Formula	C8H8BF3O2
Molecular Weight	203.96 g/mol
Synonyms	(3-Methyl-4-(trifluoromethyl)phenyl)boronic acid; 3-Methyl-4-(trifluoromethyl)benzeneboronic acid; 4-Trifluoromethyl-3-methylphenylboronic acid; Boronic acid, B-[3-methyl-4-(trifluoromethyl)phenyl]-; 864759-67-1; 3-Methyl-4-trifluoromethylbenzeneboronic acid
EINECS	Contact for details

Quality Control

Our 3-Methyl-4-Trifluoromethyl-Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.