Description

n-Boc-L-Proline (2,2-Dimethoxy-Ethyl)-Methylamide is a high-purity, protected amino acid derivative designed for advanced synthetic applications. This compound is a critical building block in the synthesis of complex molecules, offering precise stereochemical control and functional group compatibility. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, including peptide-based drugs and protease inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for peptide-mimetic drugs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce a protected proline derivative with an orthogonal protecting group strategy.
• Protease Inhibitor Development: Serves as a core structural component in the design and synthesis of inhibitors targeting specific proteolytic enzymes.
• Chemical Biology Research: Employed in the study of protein-protein interactions and the construction of molecular probes.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses producing specialized compounds for clients in the life sciences sector.

Basic Information

Product Name	n-Boc-L-Proline (2,2-Dimethoxy-Ethyl)-Methylamide
CAS No.	864754-41-6
Molecular Formula	C15H28N2O5
Molecular Weight	316.40 g/mol
Synonyms	1-Boc-L-Proline (2,2-dimethoxyethyl)methylamide; (S)-1-((2,2-Dimethoxyethyl)(methyl)carbamoyl)pyrrolidine-2-carboxylic acid tert-butyl ester; tert-Butyl (2S)-2-[(2,2-dimethoxyethyl)(methyl)carbamoyl]pyrrolidine-1-carboxylate; Boc-L-Pro-N(Me)(CH2CH(OCH3)2); N-Boc-L-Proline N'-methyl-N'-(2,2-dimethoxyethyl)amide
EINECS	Contact for details

Quality Control

Our n-Boc-L-Proline (2,2-Dimethoxy-Ethyl)-Methylamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.