Description

6-(Trifluoromethyl)Quinazoline-2,4(1H,3H)-Dione is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel pharmaceuticals and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials. The CAS number for this product is 864291-33-8.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of potential drug candidates, particularly kinase inhibitors and other biologically active molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the properties of the trifluoromethyl group.
• Material Science: Acts as a building block for advanced organic materials, such as organic semiconductors or liquid crystals.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis: Provided to contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring fluorinated quinazoline derivatives.

Basic Information

Product Name	6-(Trifluoromethyl)Quinazoline-2,4(1H,3H)-Dione
CAS No.	864291-33-8
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	6-(Trifluoromethyl)-1H,3H-quinazoline-2,4-dione; 6-Trifluoromethylquinazoline-2,4(1H,3H)-dione; 1H-Quinazoline-2,4-dione, 6-(trifluoromethyl)-; 6-Trifluoromethyl-2,4-dihydroxyquinazoline; 6-Trifluoromethyluracil (benzannulated analog)
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)Quinazoline-2,4(1H,3H)-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with the standards required for research and development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.