Description

4-(Isopropylamino)-2-(Trifluoromethyl)Benzonitrile is a specialized organic intermediate featuring a benzonitrile core substituted with a trifluoromethyl group and an isopropylamino moiety. This compound matters for its role as a critical building block in the synthesis of advanced molecules, particularly in the pharmaceutical and agrochemical sectors. It is needed by R&D chemists and process development scientists working on active ingredients for crop protection and novel drug candidates, where its unique trifluoromethyl group can impart desirable metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or metabolic diseases.
• Agrochemical Synthesis: Serves as a crucial building block for developing new-generation herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials that require fluorine-containing aromatic units.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis and molecular recognition studies in academic and industrial research.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	4-(Isopropylamino)-2-(Trifluoromethyl)Benzonitrile
CAS No.	864286-45-3
Molecular Formula	C11H11F3N2
Molecular Weight	228.21 g/mol
Synonyms	2-(Trifluoromethyl)-4-(isopropylamino)benzonitrile; 4-(Propan-2-ylamino)-2-(trifluoromethyl)benzonitrile; 4-Isopropylamino-2-trifluoromethylbenzonitrile; 2-Trifluoromethyl-4-isopropylaminobenzonitrile; Benzonitrile, 4-(isopropylamino)-2-(trifluoromethyl)-; 864286-45-3; 4-(Isopropylamino)-α,α,α-trifluoro-o-tolunitrile
EINECS	Contact for details

Quality Control

Our 4-(Isopropylamino)-2-(Trifluoromethyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and regulated production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.