Description

2-Amino-N-[3-(trifluoromethyl)benzyl]acetamide is a specialized organic compound featuring a benzylacetamide core substituted with a trifluoromethyl group and an amino functionality. This unique structure makes it a valuable pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Medicinal Chemistry Building Block: Used in high-throughput screening and combinatorial chemistry for drug discovery programs, leveraging the trifluoromethyl group to modulate lipophilicity and metabolic stability.
• Agrochemical Research: Serves as a synthetic intermediate in the development of new herbicides and fungicides, where the trifluoromethyl moiety can enhance biological activity.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying enzyme function and protein-ligand interactions.
• Material Science Research: Investigated as a monomer or additive for creating specialty polymers with unique surface properties or fluorinated characteristics.

Basic Information

Product Name	2-Amino-N-[3-(trifluoromethyl)benzyl]acetamide
CAS No.	864273-41-6
Molecular Formula	C10H11F3N2O
Molecular Weight	232.20 g/mol
Synonyms	2-Amino-N-[3-(trifluoromethyl)benzyl]acetamide; 2-Amino-N-[[3-(trifluoromethyl)phenyl]methyl]acetamide; Acetamide, 2-amino-N-[3-(trifluoromethyl)benzyl]-; Glycinamide, N-[3-(trifluoromethyl)benzyl]-; α-Amino-N-[3-(trifluoromethyl)benzyl]acetamide; N-(3-Trifluoromethylbenzyl)glycinamide; 864273-41-6
EINECS	Contact for details

Quality Control

Our 2-Amino-N-[3-(trifluoromethyl)benzyl]acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.