Description

2-Fluorophenylsulphur Pentafluoride is a specialized organosulfur fluoride compound of significant interest in advanced chemical synthesis. This high-value intermediate is crucial for introducing the pentafluorosulfur (SF5) group, a highly electronegative and lipophilic moiety, into target molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammation.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the SF5 group improves weatherfastness and biological activity.
• Advanced Material Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and electronic materials.
• Fluorination Reagent: Acts as a source of the SF5 group in electrophilic or radical fluorination reactions to modify complex organic molecules.
• Life Science Research: Employed in chemical biology as a probe or tag due to the distinctive properties of the SF5 group in analytical detection methods like 19F NMR.

Basic Information

Product Name	2-Fluorophenylsulphur Pentafluoride
CAS No.	864230-02-4
Molecular Formula	C6H4F6S
Molecular Weight	222.15 g/mol
Synonyms	2-Fluorophenylsulfur Pentafluoride; (2-Fluorophenyl)sulfur Pentafluoride; 1-Fluoro-2-(pentafluoro-λ6-sulfanyl)benzene; 2-Fluorobenzene-1-sulfonyl Fluoride (tautomer); SF5-Benzene, 2-fluoro-; 2-Fluoro-1-(pentafluorosulfanyl)benzene; Pentafluoro(2-fluorophenyl)-λ6-sulfane
EINECS	Contact for details

Quality Control

Every batch of 2-Fluorophenylsulphur Pentafluoride is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements of advanced synthetic applications. A detailed Certificate of Analysis (COA), including results from GC, NMR, and HPLC analyses, is supplied with each shipment to guarantee identity, purity, and lot-to-lot consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride/strong alkali reactivity profile, ensure containers are kept sealed and stored separately from basic compounds.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.5%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.