Description

4'-Fluoro-4-Biphenylsulfonic Acid is a specialized biphenyl derivative functionalized with both a sulfonic acid group and a fluorine substituent, making it a valuable intermediate in advanced organic synthesis. This compound's unique structure provides a combination of strong acidity and aromatic stability, which is critical for constructing complex molecular architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring a sulfonated biphenyl core for enhanced bioactivity or solubility.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators where the fluorine atom and sulfonic acid group contribute to product efficacy and environmental stability.
• Liquid Crystal Materials: Serves as a precursor or dopant in the production of fluorinated liquid crystals for display technologies, leveraging its rigid biphenyl structure and polar sulfonic acid group.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce sulfonic acid groups into polymers, enhancing properties like proton conductivity for fuel cell membranes or ion-exchange capacity.
• Catalyst & Ligand Preparation: Utilized in the preparation of metal-organic frameworks (MOFs) or as a precursor for sulfonated ligands in homogeneous catalysis.
• Organic Synthesis Reagent: Employed as a strong organic acid catalyst or as a versatile electrophile in cross-coupling reactions and other C-C/C-heteroatom bond-forming processes in fine chemical production.

Basic Information

Product Name	4'-Fluoro-4-Biphenylsulfonic Acid
CAS No.	864061-68-7
Molecular Formula	C12H9FO3S
Molecular Weight	252.26 g/mol
Synonyms	4-Fluoro-4'-biphenylsulfonic Acid; [1,1'-Biphenyl]-4-sulfonic acid, 4'-fluoro-; 4'-Fluorobiphenyl-4-sulfonic Acid; p-Fluorobiphenyl-4'-sulfonic Acid; 4-(4-Fluorophenyl)benzenesulfonic Acid; 4-Fluoro-1,1'-biphenyl-4'-sulfonic Acid; (4'-Fluoro[1,1'-biphenyl]-4-yl)sulfonic Acid
EINECS	Contact for details

Quality Control

Our 4'-Fluoro-4-Biphenylsulfonic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR). We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality system is designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its strong acid nature, keep away from incompatible materials such as strong bases, oxidizing agents, and reactive metals. The container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.