Description

3,5-Difluorophenylboronic Acid,Pinacol Ester is a high-purity, synthetically valuable organoboron reagent. This compound is a critical building block in modern organic synthesis, particularly for the formation of carbon-carbon bonds via cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require precise and reliable intermediates for constructing complex fluorinated aromatic structures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for synthesizing biaryl compounds, which are core structures in many active pharmaceutical ingredients (APIs) and agrochemicals.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, especially those incorporating difluorophenyl motifs for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy.
• Liquid Crystal & OLED Material Production: Employed in the synthesis of fluorinated organic semiconductors and display materials.
• Polymer Chemistry: Facilitates the creation of specialty polymers with tailored properties through polymerization or post-polymerization modification.
• Chemical Research & Development: A versatile tool in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	3,5-Difluorophenylboronic Acid,Pinacol Ester
CAS No.	863868-36-4
Molecular Formula	C12H15BF2O2
Molecular Weight	240.06 g/mol
Synonyms	3,5-Difluorophenylboronic Acid Pinacol Ester; 2-(3,5-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3,5-Difluorophenyl)boronic Acid Pinacol Ester; 3,5-Difluorophenyl-1,3,2-dioxaborolane, 4,4,5,5-tetramethyl-2-(3,5-difluorophenyl)-; Pinacol 3,5-Difluorophenylboronate; 3,5-Difluorophenyl-Bpin; B-(3,5-Difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 3,5-Difluorophenylboronic Acid,Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry for comprehensive characterization. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.