Description

4-Bromo-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is a high-value boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecules. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for constructing biaryl and heterobiaryl scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific halogenated and nitrile-substituted aromatic structures.
• Organic Light-Emitting Diodes (OLEDs): Building block for creating electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Polymer and Material Science: Incorporated into monomers for producing high-performance polymers with tailored electronic or thermal properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	4-Bromo-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile
CAS No.	863868-20-6
Molecular Formula	C₁₃H₁₅BBrNO₂
Molecular Weight	308.98 g/mol
Synonyms	2-Bromo-4-cyanophenylboronic acid pinacol ester; 4-Bromo-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; (4-Bromo-2-cyanophenyl)boronic acid pinacol ester; 2-Cyano-5-bromophenylboronic acid pinacol ester; 863868-20-6; Pinacol (4-Bromo-2-cyanophenyl)boronate; 4-Bromo-2-cyanobenzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.