Description

2-(Benzyloxy)-3-Bromobenzonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzonitrile core functionalized with bromine and benzyloxy groups. This compound matters for its critical role as a versatile building block in the synthesis of complex organic molecules, particularly active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalytic processes and material science.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to construct complex biaryl and heterocyclic systems.
• Material Science Research: Investigated for the preparation of organic electronic materials and liquid crystals due to its rigid, substituted aromatic framework.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in manufacturing.

Basic Information

Product Name	2-(Benzyloxy)-3-Bromobenzonitrile
CAS No.	862992-93-6
Molecular Formula	C14H10BrNO
Molecular Weight	288.14 g/mol
Synonyms	3-Bromo-2-(phenylmethoxy)benzonitrile; 2-Benzyloxy-3-bromobenzonitrile; 3-Bromo-2-benzyloxybenzonitrile; Benzonitrile, 3-bromo-2-(phenylmethoxy)-; 2-(Benzyloxy)-3-bromobenzonitrile; 862992-93-6; 3-Bromo-2-(benzyloxy)benzonitrile; 2-(Phenylmethoxy)-3-bromobenzonitrile
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-3-Bromobenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.