Description

Tris-Nta Per-tert-Butyl Ester CAS NO 862778-57-2 is a protected derivative of nitrilotriacetic acid (NTA), featuring tert-butyl ester groups that enhance its stability and solubility in organic solvents. This compound serves as a crucial advanced intermediate in organic synthesis, particularly for the controlled introduction of chelating functionalities. It is primarily utilized by pharmaceutical researchers and specialty chemical manufacturers developing novel metal-chelating agents, linkers for bioconjugation, and complexing agents for diagnostic applications.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel chelator-drug conjugates and targeted therapeutic agents.
• Ligand Synthesis: Precursor for creating specialized polydentate ligands used in catalysis and metal ion separation processes.
• Bioconjugation Linker: Used to attach chelating groups to antibodies, proteins, or other biomolecules for diagnostic and research purposes.
• Polymer Modification: Incorporation into polymer backbones to impart metal-binding properties for specialized filtration or sensing materials.
• Research & Development: Valuable reagent in academic and industrial R&D for studying metal coordination chemistry and developing new functional materials.

Basic Information

Item	Details
Product Name	Tris-Nta Per-tert-Butyl Ester
CAS No.	862778-57-2
Molecular Formula	C21H39NO6
Molecular Weight	401.54 g/mol
Synonyms	Tris(tert-butyl) nitrilotriacetate; Nitrilotriacetic Acid Tris(1,1-Dimethylethyl) Ester; NTA Tris-tert-Butyl Ester; tert-Butyl NTA Ester; 2,2',2''-Nitrilotriacetic Acid Tri-tert-butyl Ester; Tris(tert-butyl) 2,2',2''-Nitrilotriacetate; NTA-Tris(O-t-butyl) Ester; NTA-tBu3
EINECS	Contact for details

Quality Control

Our Tris-Nta Per-tert-Butyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request, supporting compliance with rigorous R&D and cGMP standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.