Description

5-Bromo-2-Hydroxy-3-Nitrobenzonitrile CAS NO 862728-34-5 is a versatile halogenated aromatic nitrile derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring bromo, hydroxy, and nitro substituents, makes it a valuable building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for molecules targeting specific enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and insecticides, leveraging its halogen and nitro groups for bioactivity.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and advanced polymers due to its electron-withdrawing nitro and nitrile groups.
• Dye and Pigment Chemistry: Intermediate for creating specialized azo dyes and pigments where the bromo and nitro groups influence color and lightfastness properties.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes and tags used in biochemical assays and diagnostic research.
• Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form biaryl structures.

Basic Information

Product Name	5-Bromo-2-Hydroxy-3-Nitrobenzonitrile
CAS No.	862728-34-5
Molecular Formula	C7H3BrN2O3
Molecular Weight	243.02 g/mol
Synonyms	3-Nitro-5-bromo-2-hydroxybenzonitrile; 2-Hydroxy-3-nitro-5-bromobenzonitrile; 5-Bromo-2-hydroxy-3-nitrobenzonitrile; Benzonitrile, 5-bromo-2-hydroxy-3-nitro-; 862728-34-5; 5-Bromo-3-nitro-2-hydroxybenzonitrile; 2-Cyano-4-bromo-6-nitrophenol
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Hydroxy-3-Nitrobenzonitrile is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.