Description

n-Methyl-D-Tryptophan CAS NO 862504-05-0 is a high-purity, non-natural amino acid derivative characterized by its methylated indole side chain and D-configuration. This compound is a critical chiral building block and intermediate in advanced pharmaceutical research and development, particularly for the synthesis of peptides and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-quality, stereochemically defined intermediates for drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and for probing protein structure-function relationships.
• Peptide Synthesis: Serves as a specialized, methylated D-tryptophan residue in the solid-phase or solution-phase synthesis of complex peptides.
• Drug Discovery: Employed in medicinal chemistry programs to create analogs for screening against various biological targets.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Asymmetric Synthesis: Acts as a chiral auxiliary or starting material in the preparation of other enantiomerically pure compounds.

Basic Information

Product Name	n-Methyl-D-Tryptophan
CAS No.	862504-05-0
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	D-N(alpha)-Methyltryptophan; (R)-2-Amino-3-(1H-indol-3-yl)-2-methylpropanoic acid; D-α-Methyltryptophan; Methyl-D-tryptophan; 1H-Indole-3-propanoic acid, α-amino-α-methyl-, (alphaR)-; N-Methyl-D-abrine
EINECS	Contact for details

Quality Control

Our n-Methyl-D-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and specific tests is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.