Description

(3As,4S,6Ar)-n-[2-[2-(2-Aminoethoxy)Ethoxy]Ethyl]Hexahydro-2-Oxo-1H-Thieno[3,4-D]Imidazole-4-Pentanamide Monohydrochloride is a high-purity, chemically defined intermediate with significant utility in advanced pharmaceutical synthesis. This compound matters for its role as a sophisticated building block in the development of novel therapeutic agents, particularly those targeting specific enzymatic pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of complex molecules for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Bioconjugation Chemistry: Utilized in the development of antibody-drug conjugates (ADCs) and other targeted drug delivery systems due to its functionalized linker structure.
• Peptidomimetic Research: Serves as a constrained scaffold in the design and synthesis of peptide analogs and mimetics for biological evaluation.
• Chemical Biology Probes: Used in the creation of molecular probes for studying enzyme function and cellular signaling pathways.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex target molecules.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge medicinal chemistry programs.

Basic Information

Product Name	(3As,4S,6Ar)-n-[2-[2-(2-Aminoethoxy)Ethoxy]Ethyl]Hexahydro-2-Oxo-1H-Thieno[3,4-D]Imidazole-4-Pentanamide Monohydrochloride
CAS No.	862373-14-6
Molecular Formula	C18H32ClN5O5S
Molecular Weight	473.99 g/mol
Synonyms	Biotin-PEG2-Amine hydrochloride; Biotin-PEG2-NH2 HCl; Biotinamidohexanoic acid-PEG2-amine hydrochloride; 6-((6-((2-(2-Aminoethoxy)ethoxy)ethyl)amino)-6-oxohexyl)carbamoyl)-5-(3-methylbutyl)thiophene-2-carboxylic acid hydrochloride; Biotin-PEG2-NH2 hydrochloride; Biotinylated PEG2 amine HCl; N-(2-(2-(2-Aminoethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to a quality management system suitable for supplying materials for research and development use under cGMP-like controls where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. This material is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed container to reach ambient temperature before opening to minimize moisture condensation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.