Description

(R)-3-Amino-1-(tert-Butoxycarbonyl)Piperidine-3-Carboxylic Acid is a high-value, non-natural amino acid derivative featuring both a Boc-protected amine and a carboxylic acid functional group on the same carbon atom. This compound is a critical chiral building block for the synthesis of complex molecules, offering precise stereochemical control. It is primarily utilized by pharmaceutical and biotechnology research organizations for the development of active pharmaceutical ingredients (APIs), peptide mimetics, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) and metabolic disease targets.
• Peptidomimetic Synthesis: Used to construct constrained peptide analogs and macrocycles by incorporating a rigid, functionalized piperidine scaffold.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and the cGMP production of advanced intermediates.

Basic Information

Product Name	(R)-3-Amino-1-(tert-Butoxycarbonyl)Piperidine-3-Carboxylic Acid
CAS No.	862372-86-9
Molecular Formula	C11H20N2O4
Molecular Weight	244.29 g/mol
Synonyms	(R)-3-Amino-1-Boc-piperidine-3-carboxylic acid; (3R)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-3-piperidinecarboxylic acid; (R)-1-Boc-3-amino-piperidine-3-carboxylic acid; (R)-1-N-Boc-3-aminopiperidine-3-carboxylic acid; (R)-3-Amino-1-(Boc)piperidine-3-carboxylic acid; (R)-3-Amino-N-Boc-piperidine-3-carboxylic acid; 1-Boc-3-amino-3-piperidinecarboxylic acid, (R)-; 862372-86-9
EINECS	Contact for details

Quality Control

Our (R)-3-Amino-1-(tert-Butoxycarbonyl)Piperidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC to ensure enantiomeric purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing purity, assay, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.