Description

Benzonitrile, 3-Chloro-5-Fluoro-2-Hydroxy- is a high-purity, halogenated benzonitrile derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate, enabling the construction of complex molecules with specific biological activity. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the chloro-fluoro-hydroxy substitution pattern is beneficial.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers.
• Chemical Reference Standard: Used as a high-purity standard in analytical laboratories for method development and quality control.

Basic Information

Product Name	Benzonitrile, 3-Chloro-5-Fluoro-2-Hydroxy-
CAS No.	862088-18-4
Molecular Formula	C7H3ClFNO
Molecular Weight	171.56 g/mol
Synonyms	3-Chloro-5-Fluoro-2-Hydroxybenzonitrile; 2-Hydroxy-3-chloro-5-fluorobenzonitrile; 3-Chloro-5-fluorosalicylonitrile; 2-Cyano-6-chloro-4-fluorophenol; 6-Chloro-4-fluoro-2-hydroxybenzonitrile; 2-Hydroxy-3-chloro-5-fluorophenyl cyanide; CAS 862088-18-4
EINECS	Contact for details

Quality Control

Our Benzonitrile, 3-Chloro-5-Fluoro-2-Hydroxy- is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to ensure traceability and compliance with your R&D and cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.