Description

3,5-Difluoro-2-Methylsulfanylphenylboronic Acid is a high-purity organoboron building block essential for modern synthetic chemistry. Its value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex biaryl and heterobiaryl structures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides with enhanced activity and environmental profile.
• Material Science Research: Serves as a precursor for creating fluorinated organic electronic materials, such as OLED emitters and charge transport layers.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to create fluorinated molecular probes for studying biological systems and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical reagent for CROs and CDMOs serving the global life sciences market.

Basic Information

Item	Details
Product Name	3,5-Difluoro-2-Methylsulfanylphenylboronic Acid
CAS No.	861931-32-0
Molecular Formula	C7H7BF2O2S
Molecular Weight	203.99 g/mol
Synonyms	(3,5-Difluoro-2-(methylthio)phenyl)boronic acid; 2-(Methylthio)-3,5-difluorophenylboronic acid; 3,5-Difluoro-2-(methylmercapto)benzeneboronic acid; 3,5-Difluoro-2-(methylsulfanyl)benzeneboronic acid; 2-Methylsulfanyl-3,5-difluorophenylboronic acid; Boronic acid, B-[3,5-difluoro-2-(methylthio)phenyl]-; 861931-32-0
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-2-Methylsulfanylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.