Description

2-(2-Fluoro-Phenyl)-2-Methylpropionic Acid Methyl Ester is a high-purity fluorinated organic ester building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine moiety enhances product efficacy and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a fluorinated intermediate in the manufacture of specialty electronic chemicals for display and lighting technologies.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for method development, including cross-coupling reactions and asymmetric synthesis.
• Fine Chemical Production: Utilized as a versatile synthon for creating complex fluorinated fragrances, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	2-(2-Fluoro-Phenyl)-2-Methylpropionic Acid Methyl Ester
CAS No.	861901-19-1
Molecular Formula	C11H13FO2
Molecular Weight	196.22 g/mol
Synonyms	Methyl 2-(2-Fluorophenyl)-2-methylpropanoate; 2-Methyl-2-(2-fluorophenyl)propionic Acid Methyl Ester; α,α-Dimethyl-2-fluorobenzeneacetic Acid Methyl Ester; 2-Fluoro-α,α-dimethylbenzeneacetic Acid Methyl Ester; Methyl α,α-Dimethyl-2-fluorophenylacetate; 861901-19-1; 2-(2-Fluorophenyl)-2-methylpropanoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 2-(2-Fluoro-Phenyl)-2-Methylpropionic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring GMP-grade intermediates and ensures consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.