Description

4-Cyano-3,5-Difluorophenylboronic Acid CAS NO 861710-03-4 is a high-value, multi-functional boronic acid derivative serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both cyano and difluoro substituents on the phenyl ring, makes it an essential reagent for constructing complex molecules via cross-coupling reactions. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing the difluorophenyl moiety into active molecules, enhancing their biological activity and metabolic stability.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where its electronic properties are leveraged.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and sensors for studying biological processes.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs serving the global life sciences market.

Basic Information

Product Name	4-Cyano-3,5-Difluorophenylboronic Acid
CAS No.	861710-03-4
Molecular Formula	C7H4BF2NO2
Molecular Weight	182.93 g/mol
Synonyms	(4-Cyano-3,5-difluorophenyl)boronic acid; 3,5-Difluoro-4-cyanophenylboronic acid; B-(4-Cyano-3,5-difluorophenyl)boronic acid; 4-Cyano-3,5-difluorobenzeneboronic acid; 861710-03-4; Boronic acid, B-(4-cyano-3,5-difluorophenyl)-; (3,5-Difluoro-4-cyanophenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 4-Cyano-3,5-Difluorophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.