Description

n-(4-Iodo-3-Nitrophenyl)Acetamide is a specialized aromatic acetamide derivative, distinguished by its iodine and nitro substituents which make it a valuable synthetic intermediate. This compound is engineered for high-precision applications where its unique halogenated nitroaromatic structure is essential for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for use in cross-coupling reactions, medicinal chemistry, and the synthesis of advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific receptors or enzymes.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, dyes, and pigments due to its electron-withdrawing nitro and iodine groups.
• Cross-Coupling Reactions: Acts as a crucial substrate in palladium-catalyzed reactions, such as Suzuki, Sonogashira, or Buchwald-Hartwig couplings, to form complex biaryl structures.
• Medicinal Chemistry & Drug Discovery: Employed in structure-activity relationship (SAR) studies and library synthesis for screening new therapeutic candidates.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	n-(4-Iodo-3-Nitrophenyl)Acetamide
CAS No.	861523-55-9
Molecular Formula	C8H7IN2O3
Molecular Weight	306.06 g/mol
Synonyms	N-Acetyl-4-iodo-3-nitroaniline; 4'-Iodo-3'-nitroacetanilide; 2-Acetamido-4-iodonitrobenzene; Acetamide, N-(4-iodo-3-nitrophenyl)-; 1-(4-Iodo-3-nitrophenyl)ethan-1-one amine; N-(4-Iodo-3-nitro-phenyl)-acetamide; 4-Iodo-3-nitroacetanilide
EINECS	Contact for details

Quality Control

Our n-(4-Iodo-3-Nitrophenyl)Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.