Description

1H-Indazole-4-Carbonitrile CAS NO 861340-10-5 is a high-purity, nitrogen-containing heterocyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceutical agents and agrochemicals, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, particularly in the discovery of kinase inhibitors and other biologically active small molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for targeted cancer therapies.
• Agrochemical Synthesis: Used in the creation of novel pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Material Science Research: Serves as a precursor for functional organic materials, including ligands for catalysis and organic semiconductors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploratory chemistry.

Basic Information

Item	Details
Product Name	1H-Indazole-4-Carbonitrile
CAS No.	861340-10-5
Molecular Formula	C8H5N3
Molecular Weight	143.15 g/mol
Synonyms	4-Cyano-1H-indazole; 1H-Indazole-4-carbonitrile; 4-CN-1H-Indazole; Indazole-4-carbonitrile; 4-Cyanindazole; 4-Cyanoindazole; 1H-Indazol-4-yl cyanide; 861340-10-5
EINECS	Contact for details

Quality Control

Our 1H-Indazole-4-Carbonitrile is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.