Description

Zomepirac Acyl-o-β-D-Glucuronide 2-Propenyl Ester is a chemically modified metabolite of the non-steroidal anti-inflammatory drug (NSAID) zomepirac. This compound is of significant value as a high-purity reference standard and a critical intermediate in pharmaceutical research and development. It is primarily needed by analytical laboratories, contract research organizations (CROs), and pharmaceutical companies engaged in drug metabolism and pharmacokinetic (DMPK) studies, bioanalytical method development, and impurity profiling.

Application

• Primary use as an analytical reference standard for the quantification of zomepirac metabolites in biological matrices.
• Critical intermediate in synthetic chemistry for the preparation of other glucuronide conjugates or labeled analogs.
• Essential component in pharmaceutical impurity identification and characterization studies to meet ICH guidelines.
• Used in metabolite safety assessment (MIST) and toxicology studies during drug development.
• Valuable reagent for method validation in high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS/MS) assays.
• Supports academic research investigating the metabolic pathways and stability of carboxylic acid-containing drugs.

Basic Information

Product Name	Zomepirac Acyl-o-β-D-Glucuronide 2-Propenyl Ester
CAS No.	860615-41-4
Molecular Formula	C25H29NO10
Molecular Weight	503.50 g/mol
Synonyms	Zomepirac Acyl Glucuronide 2-Propenyl Ester; Zomepirac 1-O-β-Acyl Glucuronide Allyl Ester; 5-(1,4-Dimethyl-1H-pyrrol-2-yl)-1-(4-methoxyphenyl)-3-(2-propenyloxy)-3,4-dideoxy-4-[[(2,3,4-trihydroxy-5-oxopentyl)oxy]carbonyl]-β-D-erythro-hex-3-enopyranosiduronic Acid; Allyl Zomepirac Acyl-β-D-glucuronide; Zomepirac Acyl-β-D-glucuronide Allyl Ester; ZAG Allyl Ester
EINECS	Contact for details

Quality Control

Our Zomepirac Acyl-o-β-D-Glucuronide 2-Propenyl Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by HPLC, NMR, and mass spectrometry. We adhere to ISO 9001 quality management principles, and our processes are designed to support compliance with cGMP for APIs and ICH Q3A/B guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, ideally between 15-25°C (59-77°F), in a dry environment. For long-term storage, consider storing at -20°C under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.