Description

2-(Boc-Amino)-Cyclopentanemethanamine is a protected amino acid derivative featuring a cyclopentane backbone and a Boc-protected primary amine. This compound is a crucial chiral building block in organic synthesis, valued for its role in constructing complex molecular architectures with defined stereochemistry. It is primarily needed by pharmaceutical R&D and fine chemical synthesis teams for the development of active pharmaceutical ingredients (APIs), peptide mimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptidomimetics & Conformational Studies: Used to introduce constrained, non-natural amino acid residues into peptide chains to enhance stability, bioavailability, and biological activity.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Ligand & Catalyst Development: Employed in the construction of novel chiral ligands and organocatalysts for use in stereoselective transformations.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental building block supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-(Boc-Amino)-Cyclopentanemethanamine
CAS No.	860297-27-4
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1-[(1,1-Dimethylethoxy)carbonyl]amino]-2-(aminomethyl)cyclopentane; 2-(Boc-amino)cyclopentanemethanamine; 2-(tert-Butoxycarbonylamino)cyclopentanemethanamine; (2-Aminomethylcyclopentyl)carbamic acid tert-butyl ester; N-Boc-2-aminomethylcyclopentylamine; Boc-Cyp-NH2; Cyclopentanemethanamine, 2-[(tert-butoxycarbonyl)amino]-; 860297-27-4
EINECS	Contact for details

Quality Control

Our 2-(Boc-Amino)-Cyclopentanemethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.