Description

Mandelamide, m-Chloro- (3Ci) is a specialized chlorinated mandelamide derivative, a key chiral intermediate in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. Industries requiring high-purity chiral building blocks, such as pharmaceutical R&D, agrochemical synthesis, and specialty chemical manufacturing, are the primary users of this material. Its defined stereochemistry and functional groups make it a valuable precursor for targeted synthesis.

Application

• Pharmaceutical Intermediate: A crucial chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry influences biological activity.
• Fine Chemical Production: Serves as a precursor for synthesizing complex flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial Research: A valuable reagent in methodological development for asymmetric synthesis and catalysis studies.
• Ligand and Catalyst Preparation: Utilized in the design and synthesis of chiral ligands for metal-catalyzed asymmetric reactions.

Basic Information

Product Name	Mandelamide, m-Chloro- (3Ci)
CAS No.	859931-64-9
Molecular Formula	C9H10ClNO2
Molecular Weight	199.63 g/mol
Synonyms	(R/S)-2-Amino-2-(3-chlorophenyl)acetic acid amide; 3-Chloromandelamide; (±)-2-Amino-2-(3-chlorophenyl)acetamide; α-Amino-3-chlorobenzeneacetamide; m-Chloro-mandelic acid amide; (3-Chlorophenyl)(cyano)methanamine oxide (related); Mandelic acid amide, 3-chloro-
EINECS	Contact for details

Quality Control

Every batch of Mandelamide, m-Chloro- (3Ci) is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive testing includes identity confirmation, chiral purity, chemical assay, and impurity profiling. Certificates of Analysis (COA) detailing all specifications and test results are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.