Description

2-Bromo-4-Chloro-6-Fluorobenzonitrile is a high-purity halogenated benzonitrile derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its multi-substituted aromatic structure makes it a valuable building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Liquid Crystal & OLED Material Research: Serves as a core building block for creating novel electron-transport materials and liquid crystal compounds in display technology.
• Organic Synthesis & Catalysis: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a substrate for developing new catalytic methodologies.
• Polymer & Material Science: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or optical properties.
• Chemical Research & Development: Essential for academic and industrial R&D in exploring new chemical spaces and structure-activity relationships (SAR).

Basic Information

Item	Details
Product Name	2-Bromo-4-Chloro-6-Fluorobenzonitrile
CAS No.	858414-22-9
Molecular Formula	C7H2BrClFN
Molecular Weight	234.45 g/mol
Synonyms	2-Bromo-4-chloro-6-fluorobenzonitrile; Benzonitrile, 2-bromo-4-chloro-6-fluoro-; 2-Bromo-4-chloro-6-fluorophenyl cyanide; 858414-22-9; 6-Fluoro-2-bromo-4-chlorobenzonitrile; 4-Chloro-2-bromo-6-fluorobenzonitrile; 2-Bromo-4-chloro-6-fluoro-benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Chloro-6-Fluorobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.